Aloe — the dried, concentrated juice of the leaf of Aloe vera (L.) Burm. f. or of Aloe ferox Mill. (family Asphodelaceae). The drug is the bitter yellow latex that lies just under the leaf skin; it is not the clear inner gel sold in cosmetics.
Nature and flavour. Bitter, cold. Liver, Stomach and Large Intestine systems.
Like senna, a drug that reached Chinese materia medica from the west rather than from the classical canon, and which the sources record for two apparently unrelated things: constipation of the heat type, and the traditional pattern of liver fire with irritability, red eyes and constipation together. It is also used externally for burns, sores and cracked skin. The double life of this plant is why people confuse it: the gel inside the leaf is a cosmetic and a soothing dressing, while the drug is the bitter latex between the gel and the skin. The two are not the same material and do not have the same effects. The laxative action is the anthraquinones — aloin and its relatives — and it works in the way senna works. The clearing-liver indications belong to classical theory and are not established.
性味归经。苦,寒。归肝、胃、大肠经。
与番泻叶一样,是从西方进入本草而非出自古典经典的一味药。文献记载它用于两件似乎不相干的事:热结便秘,以及古籍所称肝火所致的烦躁、目赤与便秘并见。外用则治烧烫伤、疮疡与皮肤皲裂。这株植物的「双重身份」正是人们混淆的原因:叶内的凝胶是化妆品与舒缓敷料,而药是凝胶与表皮之间那层苦味的汁液。两者不是同一种材料,作用也不同。泻下作用来自蒽醌类(芦荟苷等),其效力机制与番泻叶同类。清肝一类主治属于古典理论,尚未被证实。
在看芦荟的任何功效说法之前,先读这一段。有两项监管判决定案在册。美国食品药品管理局在 2002 年定稿的 OTC(柜台成药)泻药专论中,把芦荟汁与波希鼠李皮从专论中剔除:该局要求的安全性数据厂商未提供,因此在美国,芦荟的刺激性泻下用途不属于被认可的柜台成药用途。国际癌症研究机构在 2016 年将未脱色的芦荟全叶提取物列为「可能对人类致癌」(2B 类),依据为有限证据;其背后的动物实验用的是全叶提取物,不是凝胶。这个结论是需要谨慎的理由,而不是对人有害的证明。此外:汁液是刺激性泻药,后果与同类药物一样——绞痛、水泻、丢钾,以及肠道最终依赖它。不宜每日或长期服用。腹痛原因未明、疑似肠梗阻、阑尾炎或炎症性肠病者禁用。孕期、哺乳期与儿童列为禁忌:它是传统的子宫兴奋药,且蒽醌类会进入乳汁。外用芦荟凝胶可引起接触性皮炎,把它用在较深或已严重感染的伤口上是错误的决定。新近出现的便秘,或伴体重下降、便血的便秘,应当去检查,而不是去找一片叶子。