Knowledge Base/Formulas/Da Ding Feng Zhu
Educational and cultural reference only — not medical advice. We do not diagnose, do not prescribe, do not recommend medicines or doses, and make no claim to treat or cure any condition. Nothing here should delay you from seeking care. If you have a health concern, consult a licensed healthcare professional.
滋阴息风;传统用于温病后期真阴耗伤、虚风内动,症见手足瘛疭、神倦、脉气虚弱 · Nourishes yin and extinguishes wind; the classical formula for the late stage of warm disease when true yin is consumed and wind stirs inwardly

Da Ding Feng Zhu (Major Wind-Stabilising Pearl) dà dìng fēng zhū · 大定风珠

Composition 组成

  • White peony root (bai shao)
  • donkey-hide gelatin (e jiao)
  • turtle shell (gui ban)
  • dried rehmannia root (sheng di huang)
  • hemp seed (huo ma ren)
  • schisandra fruit (wu wei zi)
  • oyster shell (mu li)
  • ophiopogon tuber (mai dong)
  • honey-fried licorice root (zhi gan cao)
  • egg yolk (ji zi huang)
  • turtle carapace (bie jia).

组成

  • 白芍、阿胶、龟板、生地黄(原方作干地黄)、麻仁(火麻仁)、五味子、牡蛎、麦冬、炙甘草、鸡子黄、鳖甲
Source 出处 · Wenbing Tiaobian · Doses are not given here: they are set by a licensed practitioner for the individual.
Safety. Da Ding Feng Zhu comes from Wenbing Tiaobian, Wu Tang's nineteenth-century treatise on warm disease, and it sits at the end of a chain rather than standing alone. The base is jia jian fu mai tang — the honey-fried licorice decoction with the warming and moving ingredients removed and white peony added. To that are added the three shells: turtle shell, turtle carapace and oyster shell. Then donkey-hide gelatin and egg yolk are added last. The three shells are heavy, mineralised animal materials traditionally described as anchoring and settling what has risen; the gelatin and the yolk belong to what classical language calls flesh-and-blood products, used because the depletion being addressed is understood as a loss of substance rather than a blockage to be moved. The pattern being treated, wind stirring inwardly from depleted yin, is a piece of classical mechanism and not a diagnosis. In practice what it described was tremor, twitching or carpopedal spasm late in a prolonged febrile illness, with exhaustion and a weak pulse. The honest modern translation is that this is a differential, and a broad one. Twitching and tremor arise from electrolyte disturbance — low calcium, low magnesium, low sodium; from hepatic and renal encephalopathy; from focal seizures; from drugs, including the extrapyramidal effects of antipsychotics, metoclopramide and some antihistamines; from withdrawal states; from hypoglycaemia; and from thyrotoxicosis. In a child a febrile seizure is common and usually benign, but fever with a seizure still has to be distinguished from meningitis and encephalitis, and neck stiffness, altered consciousness or a rash that does not blanch is measured in minutes. A first seizure in an adult is a reason for imaging and electroencephalography, not for a framework about wind. This library does not present the formula as a treatment for epilepsy, Parkinson's disease or any movement disorder. The safety list is dominated by the fact that this is a formula made largely of animal materials. Turtle shell and turtle carapace come from turtles, and most turtle species are listed under CITES, which makes international trade in them a permit matter as well as a conservation one — and means an unlabelled product carries an origin question with it. Donkey-hide gelatin is made by boiling donkey hide; it is an animal product unsuitable for vegetarian, halal or kosher use. Egg yolk is classically added near the end rather than boiled through, and raw or lightly cooked egg carries a salmonella risk that matters most for older adults, pregnant women and immunosuppressed people. Oyster shell is a marine shell, and near-shore bivalves concentrate heavy metals. Hemp seed is the seed of the hemp plant and is a food; it is not a way of consuming cannabis, but it can produce a positive urine test for cannabinoid metabolites in some people. Among the herbs, schisandra has been shown in laboratory work to inhibit CYP3A4 and P-glycoprotein, and interactions with tacrolimus, ciclosporin and some chemotherapy agents have been studied — that is a reason to tell the prescribing clinician rather than a reason for alarm. White peony and its standardised glucoside fraction have been associated with liver enzyme elevation and diarrhoea. Honey-fried licorice carries the familiar glycyrrhizin risk of low potassium, raised blood pressure and oedema. The rehmannia used here is the unprepared dried root, not the wine-steamed prepared form. This library gives no amounts.

大定风珠出自吴瑭十九世纪的温病学著作《温病条辨》。它不是一首孤立的方,而处在一串加减的末端:底方是加减复脉汤(炙甘草汤减去温通走散之品、加白芍),其上加「三甲」—— 龟板、鳖甲、牡蛎,最后再加阿胶与鸡子黄。三甲是重坠的、含钙质的动物甲壳类,传统说它们潜镇沉降;阿胶与鸡子黄属于古典语言所说的「血肉有情之品」,用它俩的理由是:此处所补之虚被理解为一种「物质之失」,而不是需要被推动的阻滞。 它所对的证 —— 真阴耗伤、虚风内动 —— 是一段古典病机推演,不是诊断。落到临床上,它描述的是久热之后的手足蠕动或瘛疭,伴神倦与脉虚。诚实的现代翻译是:这是一个鉴别清单,而且很宽。抽动与震颤可来自电解质紊乱(低钙、低镁、低钠);来自肝性与肾性脑病;来自局灶性癫痫发作;来自药物,包括抗精神病药、甲氧氯普胺与某些抗组胺药的锥体外系反应;来自戒断状态;来自低血糖;也来自甲状腺毒症。儿童的发热惊厥常见且通常良性,但发热伴抽搐仍需与脑膜炎、脑炎区分,颈强直、意识改变或压之不褪色的皮疹按分钟计。成人首次发作抽搐是做影像与脑电图的理由,而不是谈论「风」的场合。本库不声称此方治疗癫痫、帕金森病或任何运动障碍。 安全提示被一个事实主导:这首方大半由动物来源之物组成。龟板与鳖甲取自龟鳖,而多数龟鳖被列入 CITES,其国际贸易既是许可问题也是保护问题 —— 这意味着来源不明的产品自带一个「它从哪来」的疑问。阿胶由驴皮熬制,是动物制品,素食、清真、洁食均不宜。鸡子黄按传统是后下而非久煮,生的或半熟的蛋带有沙门氏菌风险,对老人、孕妇与免疫抑制者最要紧。牡蛎是海产贝壳,近岸双壳类会富集重金属。火麻仁是大麻的种子,是食物,不是摄入大麻的方式,但可让部分人尿检大麻代谢物呈阳性。 药味方面:五味子在实验室研究中显示抑制 CYP3A4 与 P-糖蛋白,与他克莫司、环孢素及部分化疗药的相互作用被研究过 —— 这是要告知处方医生的理由,不是惊慌的理由。白芍及其标准化的白芍总苷有肝酶升高与腹泻的报告。炙甘草仍是那条熟悉的甘草酸风险:血钾下降、血压升高、水肿。此处地黄用的是干地黄(生地黄),不是熟地黄。本库不列用量。

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